Process for the preparation of liposomes in aqueous solution
Method of encapsulating biologically active materials in lipid vesicles
Process for making lipid membrane structures Patent #: 4394372
ApplicationNo. 06/521176 filed on 08/08/1983
US Classes:424/1.21, Molecular bilayer structure (e.g., vesicle, liposome)264/4.6, Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)424/450, Liposomes428/402.2, Microcapsule with fluid core (includes liposome)436/829LIPOSOMES (E.G., ENCAPSULATION, ETC.)
ExaminersPrimary: Nucker, Christine M.
Attorney, Agent or Firm
International ClassA61K 9/127 (20060101)
AbstractA process for the preparation in a monophasic solvent system of a new type of lipid vesicles, called monophasic lipid vesicles (MPVs). MPVs can be made to encapsulate one or more bioactive agents. MPVs are stable during storage and can be used in vivo in the treatment of disease.