2,4-diamino-5-(1,2,3,4-tetrahydro-(substituted or unsubstituted)-6-quinolylmethyl)pyrimidines, useful as antimicrobials
Patent 4587341 Issued on May 6, 1986. Estimated Expiration Date: 
May 6, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 6, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3819629 Benzylpyrimidines Monoheteroring compounds and their use Patent #: 4438267 InventorsApplicationNo. 06/490198 filed on 04/29/1983US Classes:544/324, Additional hetero ring which is unsaturated544/114, Diazine ring544/295, Plural diazine rings544/325, Substituent on 5-position contains carbocyclic ring546/141, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding546/145, Acyclic nitrogen double or triple bonded to carbon which is attached directly or indirectly to the isoquinoline ring system by nonionic bonding546/153, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding546/176Nitrogen, other than as nitro or nitroso, attached indirectly to the quinoline ring system by nonionic bondingExaminersPrimary: Daus, Donald G.Assistant: Shen, Cecilia Attorney, Agent or FirmInternational ClassesC07D 209/00 (20060101)C07D 403/06 (20060101) C07D 209/24 (20060101) C07D 405/00 (20060101) C07D 239/00 (20060101) C07D 405/06 (20060101) C07D 409/00 (20060101) C07D 239/48 (20060101) C07D 215/00 (20060101) C07D 215/12 (20060101) C07D 215/227 (20060101) C07D 217/00 (20060101) C07D 409/06 (20060101) C07D 217/14 (20060101) C07D 401/00 (20060101) C07D 333/00 (20060101) C07D 333/60 (20060101) C07D 401/06 (20060101) C07D 403/00 (20060101) Foreign Application Priority Data1982-05-07 GBAbstractCompounds of the formula (II) ##STR1## or a salt, N-oxide or acyl derivative thereof, wherein Y is a group ##STR2## which is optionaly substituted and which optionally contain a nitrogen atom at one of positions A, B, C, D or E, in which the dotted line represents aromatic rings unless one of the rings contains a nitrogen atom in which case this ring is either aromatic or partially saturated, have antimicrobial properties. Processes for making these compounds, pharmaceutical compositions containing them and the medical use of the compounds are also disclosed. |
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