Magnesium trisilicate suitable for preparation of medicament adsorbates

Patent 4581232 Issued on April 8, 1986. Estimated Expiration Date:

July 20, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Intramammary compositions Patent #: 4401674
Issued on: 08/30/1983
Inventor: Dowrick

Inventors

Application

No. 06/516002 filed on 07/20/1983

US Classes:

424/683Magnesium silicate

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Class

A61K 9/14 (20060101)

Abstract

A medicament adsorbate containing a magnesium trisilicate having a surface area of at least 400 m2 /g and having a flake-like structure with multiple interstitial spaces, and having adsorbed therein from about 1% to about 20% by weight of the adsorbate of a medicament drug.

Other References

Khalil et al., CA. 79, #9826n (1973) In Vitro Adsorption of Some Drugs on Antacids of Pharmazie (1973), 28 (2): 116-118
Magid et al., CA. 57, #12649b (1962) of Belg. No. 611639
Zentner, CA. 65, #578a (1966) of U.S. Pat. No. 3,248,290
Couchoud et al., CA. 78, #140400r (1973) of Fr. Dem. No. 2,128,046
El-Nakeeb et al., CA. 68, #89857j (1968) of Acta Pharm. Suecica, 5(1):1-8 (1968)
El-Masry et al., CA. 81, #41376t (1974) of J. Pharm. Pharmacol (1974) 26(4): 2438
Zheng, CA 98: 113625z (1983) of Nanjing Vaoxueyuan Xuebao 1982 (2) 51-57