Pharmaceutical compositions containing insulin
Patent 4579730 Issued on April 1, 1986. Estimated Expiration Date: 
May 9, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 9, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 06/608462 filed on 05/09/1984US Classes:424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/482, Containing solid synthetic polymers424/490, Coated (e.g., microcapsules)514/3Insulin or derivativeExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 38/55 (20060101)A61K 9/20 (20060101) A61K 9/28 (20060101) A61K 38/28 (20060101) Foreign Application Priority Data1983-05-23 ILAbstractThe invention provides a pharmaceutical composition for the oral administration of insulin comprising insulin, a bile acid or alkali metal salt thereof, the bile acid being selected from the group consisting of cholic acid, chenodeoxycholic acid, taurocholic acid, taurochenodeoxycholic acid, glycocholic acid, glycochenocholic acid, 3ଲ-hydroxy-12-ketocholic acid, 12-3ଲ-dihydrocholic acid, and ursodesoxycholic acid, and a protease inhibitor, the composition being provided with an enterocoating to assure passage through the stomach and release in the intestine.Other References
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