Process of coating particles of less than 20 microns with a polymer coating Patent #: 3992558
ApplicationNo. 06/577079 filed on 02/06/1984
US Classes:427/2.15, Fluidized bed utilized424/493, Containing polysaccharides (e.g., sugars)424/497, Containing solid synthetic polymers427/213, Fluidized bed utilized428/402.24Microcapsule with solid core (includes liposome)
ExaminersPrimary: Kittle, John E.
Assistant: Shah, Mukund J.
Attorney, Agent or Firm
International ClassesA61K 9/16 (20060101)
A61K 9/50 (20060101)
AbstractA process for preparing coated microparticles, which process comprises preparing a solvent solution of an active ingredient to be encapsulated and a film-forming polymer, removing the solvent to provide a dry, composite, uniform admixture of the active ingredient and the polymer material, reducing the composite admixture to a defined smaller particle size distribution, coating the reduced composite core particles in a fluidized bed, with a uniform defined wall thickness of the same or substantially the same film-forming polymer material to provide composite core coated microparticles.