U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Skin permeation enhancer compositions

Patent 4568343 Issued on February 4, 1986. Estimated Expiration Date: Icon_subject October 9, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3472931

3527864

3598122

3598123

3896238

3903256

Dermatological compositions
Patent #: 3952099
Issued on: 04/20/1976
Inventor: Smith

Dermatological compositions
Patent #: 4046886
Issued on: 09/06/1977
Inventor: Smith

Dermatological compositions
Patent #: 4130643
Issued on: 12/19/1978
Inventor: Smith

Dermatological compositions
Patent #: 4130667
Issued on: 12/19/1978
Inventor: Smith

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Inventors

Application

No. 06/659121 filed on 10/09/1984

US Classes:

424/449, Transdermal or percutaneous514/552, Z contains an unbroken chain of at least seven carbon atoms bonded directly to the C(=O) group514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947Topical application

Examiners

Primary: Metz, Andrew H.
Assistant: Chapman, Terryence

Attorney, Agent or Firm

International Classes

A61K 9/70 (20060101)
A61K 47/14 (20060101)

Abstract

A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with polyethylene glycol monolaurate. Preferred embodiments of transdermal therapeutic systems for delivering drug and polyethylene glycol monolaurate employ matrix containing drug at a concentration above saturation.

Other References

  • Norman F. Estrin, "CTFA Cosmetic Ingredient Dictionary", 1973, 1st Edition, pp. 126 and 127
  • Idson, "Percutaneous Absorption", Journal of Pharmaceutical Sciences, Jun. 1975, pp. 901-924
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