8-Chloro-1,5-benzothiazepine derivatives
Patent 4567175 Issued on January 28, 1986. Estimated Expiration Date: 
May 16, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 16, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References3562257 InventorsAssigneeApplicationNo. 06/610856 filed on 05/16/1984US Classes:514/211.07, Nitrogen attached directly or indirectly to the ring nitrogen of the seven-membered hetero ring by acyclic nonionic bonding (e.g., Diltiazem, etc.)540/491The chalcogen and the nitrogen are in the 1,5-positions of the bicyclo ring system (e.g., 1,5-benzothiazepinone, etc.)ExaminersPrimary: Bond, Robert T.Attorney, Agent or FirmInternational ClassesC07D 281/00 (20060101)C07D 281/10 (20060101) Foreign Application Priority Data1983-06-03 GBAbstractNovel 8-chloro-1,5-benzothiazepine derivatives of the formula: ##STR1## wherein R1 is hydrogen, lower alkyl or a group of the formula: R4 CO--, each of R2 and R3 is lower alkyl and R4 is hydrogen or lower alkyl, and a pharmaceutically acceptable acid addition salt thereof are disclosed. Said derivative (I) and a pharmaceutically acceptable acid addition salt thereof are useful as hypotensive agents and/or coronary or cerebral vasodilators. |
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