U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Active agent dispenser

Patent 4564364 Issued on January 14, 1986. Estimated Expiration Date: Icon_subject May 26, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3342183

3598127

3854480

3921636

3923939

3926188

Novel drug delivery device
Patent #: 3948262
Issued on: 04/06/1976
Inventor: Zaffaroni

Microporous drug delivery device
Patent #: 3993072
Issued on: 11/23/1976
Inventor: Zaffaroni

Antimicrobial sutures
Patent #: 4024871
Issued on: 05/24/1977
Inventor: Stephenson

Bandage for transdermally administering scopolamine to prevent nausea
Patent #: 4031894
Issued on: 06/28/1977
Inventor: Urquhart ,   et al.

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Inventors

Assignee

Application

No. 06/498381 filed on 05/26/1983

US Classes:

424/484, Matrices424/449, Transdermal or percutaneous604/304, Bandage, pad, or shield placed on body for sustained treatment thereof604/307, Adhesively attachable to body604/308Bandage, pad, shield, or attaching means extendable around body portion

Examiners

Primary: Williams, Howard L.

Attorney, Agent or Firm

International Classes

A61K 9/20 (20060101)
A61K 9/70 (20060101)
A61M 31/00 (20060101)

Abstract

The release pattern of a dispersion type active agent dispenser can be improved by forming the device from a depleted zone containing the agent at a concentration no greater than the saturation and a non-depleted zone containing the agent dispersed in the matrix at a uniform concentration greater than saturation. The depleted zone is disposed between the surface through which the agent is to be dispensed and at least a substantial portion of the non-depleted zone with the interface therebetween disposed at a non-uniform distance from the releasing surface. Certain embodiments are particularly useful for the transdermal administration of drugs.

Other References

  • Higuchi, J. Pharm. Sci., vol. 50, No. 10 (Oct., 1961), pp. 874-875
  • Higuchi, J. Pharm. Sci., vol. 52, No. 12 (Dec., 1963), pp. 1145-1149
  • Chien et al., J. Pharm. Sci., vol. 63, No. 4 (Apr., 1974), pp. 515-519
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