Inventor

• Zupan, Jacob A.

Assignee

• Merck & Co., Inc.

Application

No. 06/554026 filed on 11/21/1983

US Classes:

514/11, Monocyclic424/45, Organic pressurized fluid514/14, 12 to 15 peptide repeating units in known peptide chain514/152, 3,10-dihydroxy-2-naphthacene carboxamide or derivative (e.g., tetracycline, etc.) DOAI514/153, With stabilizer or preservative514/154, With an additional active ingredient (excludes reaction product or complex)514/155, Para-N-benzene - sulfoxy-N containing DOAI, and said benzene ring is not part of a polycyclo ring system514/192, 1-thia-4-aza-bicyclo (3.2.0) heptane ring containing (including dehydrogenated) (e.g., penicillins, etc.)514/197, 6-position substituent contains carbocyclic ring514/199, Penicillin G per se or salt thereof (e.g., procaine pencillin G, etc.)514/201, 7,7-di-substituted514/209, Alkyl, hydroxyalkyl, alkoxyalkyl, or alkanoyloxyakyl bonded directly to 3-position514/23, Carbohydrate (i.e., saccharide radical containing) DOAI514/236.2, Three or more ring hetero atoms in the additional hetero ring514/24, S-glycoside514/25, O-glycoside514/253.08, Having -C(=X)-, wherein X is chalcogen, bonded directly to carbon of the hetero ring of the quinoline ring system514/269, Pyrimidines with chalcogen bonded directly to a ring carbon of said pyrimidine moiety514/27, Oxygen of the saccharide radical bonded directly to a nonsaccharide hetero ring or a polycyclo ring system which contains a nonsaccharide hetero ring514/29, The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)514/31, The hetero ring has 20 or more ring carbons (e.g., nystatin, etc.)514/311, Quinolines (including hydrogenated)514/312, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding514/317, Additional ring containing514/358, The ring nitrogen of the six-membered hetero ring is pentavalent (e.g., quaternary pyridinium salt, etc.)514/365, 1,3-thiazoles (including hydrogenated)514/37, The nitrogen atoms are in N-C(=N)-N groups (e.g., streptomycin, etc.)514/380, Chalcogen or nitrogen bonded directly to ring carbon of the oxazole ring514/389, Divalent chalcogen or acyclic nitrogen double bonded directly at both 2- and 4- positions, or tautomeric equivalent (e.g., hydantoin, etc.)514/390, Chalcogen or nitrogen bonded directly at 1-, 3-, or 5-position by nonionic bonding514/392, Divalent chalcogen or acyclic nitrogen double bonded at 2-position, or tautomeric equivalent514/42, N-glycoside514/462, Spiro ring system514/50, 2,4-diketone pyrimidine or derivative (e.g., uracil, etc.)514/535, The nitrogen of the Z radical is directly bonded to a benzene ring which is directly bonded to the C(=O) group514/536, With an agent to enhance topical absorption or with a stabilizing agent514/553, Radical -XH acid, or anhydride, acid halide or salt thereof (X is chalcogen) DOAI514/554, Amine addition salt of the acid514/555, Benzene ring in acid moiety514/561, Nitrogen other than as nitro or nitroso nonionically bonded514/567, Benzene ring nonionically bonded514/626, Nitrogen in R514/633, Amidoximes (i.e., N-C=N-O)514/636, Polyamidines514/646, Benzene ring containing514/652, Alkanol group only between the amino nitrogen and an ether oxygen which is bonded directly to the aryl ring or aryl ring system (i.e., aryloxy alkanol amines)514/653, Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)514/657, Bicyclo ring system514/667, C-O-group containing514/714, Peroxide DOAI514/735, Nuclear halogenated514/747, Carbocyclic514/853, DECONGESTANT514/99Oxygen containing hetero ring

Examiners

Primary: Friedman, Stanley J.

Attorney, Agent or Firm

• <coma><coma>Polk; Manfred
• Sudol, Jr.; Michael C.
• Monaco; Mario A.

International Class

A61K 47/22 (20060101)