Patent ReferencesNovel drug delivery device Microporous drug delivery device Vaginal contraceptive system made from block copolymer Delivery means for biologically active agents Biocompatible material comprising a base polymer bulk graft polymerized with an ethylenically unsaturated carboxylic acid Patent #: 4377010 InventorAssigneeApplicationNo. 06/639277 filed on 08/09/1984US Classes:424/424, Membrane or diffusion barrier424/434, Mucosal (e.g., nasal, etc.)424/449, Transdermal or percutaneous424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/486Synthetic polymerExaminersPrimary: Metz, Andrew H.Assistant: Chapman, Terryence Attorney, Agent or FirmInternational ClassesA61K 9/28 (20060101)A61M 31/00 (20060101) AbstractA drug release device employing a block copolymer of poly(ether-urethane)/poly(dimethyl siloxane) is useful for dispensing lipophilic drugs at a high controlled rate for prolonged periods of time. The initial "burst effect" of drug release experienced with prior drug release devices is eliminated or at least substantially reduced with these devices. | |