Long-lasting multi-layered film preparation
Patent 4552751 Issued on November 12, 1985. Estimated Expiration Date: 
November 12, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 12, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3926188 Unit dosage forms Method of delivering drug with aid of effervescent activity generated in environment of use Drug delivery system Stabilized, prostaglandin-containing tablets with controlled rate of solubility, for local use and process for the preparation thereof Long-lasting three-layered pharmaceutical film preparations Patent #: 4483846 InventorsAssigneeApplicationNo. 06/312458 filed on 10/19/1981US Classes:424/449, Transdermal or percutaneous514/443, Polycyclo ring system having the hetero ring as one of the cyclos514/573Cyclopentyl or cyclopentene (e.g., prostaglandins, etc.)ExaminersPrimary: Kepplinger, Esther M.Assistant: Foley, Shawn P. Attorney, Agent or FirmInternational ClassesA61K 9/70 (20060101)A61K 31/557 (20060101) Foreign Application Priority Data1980-10-17 JPAbstractThe present invention provides multi-layered film preparations which comprise one or more water soluble polymer bases, one or more water insoluble polymer bases, one or more plasticizers and one or more prostaglandins, and optionally contain one or more organic acids, and they are composed of at least two drug release controlling layers and one or more drug storing layers. The multi-layered film preparations of the present invention are characterized by that the prostaglandin(s) containing therein exhibit the desired long-lasting release patterns at the concentration required for therapeutic purpose.Other References
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