Patent ReferencesInventors
AssigneeApplicationNo. 06/420384 filed on 09/20/1982US Classes:427/213.31, With post-treatment of encapsulant or encapsulating material (e.g., further coating, hardening, etc.)252/363.5, SOLIDS WITH SOLUTION OR DISPERSION AIDS424/494, Cellulose derivatives424/495, Ethyl cellulose424/496, Containing natural gums/resins427/2.16, Retarded or controlled-release layer produced (e.g., enteric)427/2.21, Retarded or controlled-release layer produced (e.g., enteric)427/213.35, Solid-walled microcapsule formed from gelatin or derivative thereof427/213.36Solid-walled microcapsule formed from preformed synthetic polymerExaminersPrimary: Lovering, Richard D.Attorney, Agent or FirmInternational ClassesA61K 9/14 (20060101)A61K 9/50 (20060101) Foreign Application Priority Data1979-04-13 JPAbstractDisclosed is a process for the preparation of an activated pharmaceutical composition containing a solid drug that is scarcely soluble in water, the pharmaceutical composition being characterized in that, when it is administered orally, the drug is readily absorbed to attain its high blood concentration quickly. This process is carried out by providing a solid drug that is scarcely soluble in water, dispersing the drug in water in the presence of a water-soluble high-molecular substance to form a disperse system containing the drug in the form of finely divided particles substantially not greater than 10μ in diameter, and then removing the water from the disperse system. | |