U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose

Patent 4540566 Issued on September 10, 1985. Estimated Expiration Date: Icon_subject April 2, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3065143

3870790

Sustained release therapeutic compositions
Patent #: 4226849
Issued on: 10/07/1980
Inventor: Schor

Method and composition for the preparation of controlled long-acting pharmaceuticals
Patent #: 4259314
Issued on: 03/31/1981
Inventor: Lowey

Pharmaceutical formulation for slow release via controlled surface erosion
Patent #: 4264573
Issued on: 04/28/1981
Inventor: Powell ,   et al.

Therapeutic compositions with enhanced bioavailability
Patent #: 4344934
Issued on: 08/17/1982
Inventor: Martin ,   et al.

Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
Patent #: 4369172
Issued on: 01/18/1983
Inventor: Schor ,   et al.

Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose Patent #: 4389393
Issued on: 06/21/1983
Inventor: Schor ,   et al.

Inventors

Application

No. 06/596095 filed on 04/02/1984

US Classes:

424/480, Cellulose or derivative514/781, Cellulose or derivative514/964SUSTAINED OR DIFFERENTIAL RELEASE TYPE

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Class

A61K 9/20 (20060101)

Abstract

A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and prolonged release pattern upon administration, the carrier base material being a mixture of one or more nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is a modified hydroxypropylmethylcellulose having a number average molecular weight of less than 50,000 and has been modified by successive or concurrent exposure to moisture and air.

Other References

  • Daly et al, Int. J. Pharm., 18(1-2):201-205 (1984) The Effect of Anionic Surfactants on the Release of Chlorpheniramine Maleate from a Polymer Matrix Tablet
  • Krycer et al., Powder Technol., 34(1):39-50 (1983) An Evaluation of Tablet Binding Agents
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?