Patent References 3065143 3870790 Sustained release therapeutic compositions Method and composition for the preparation of controlled long-acting pharmaceuticals Pharmaceutical formulation for slow release via controlled surface erosion Therapeutic compositions with enhanced bioavailability Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose Patent #: 4389393 InventorsApplicationNo. 06/596095 filed on 04/02/1984US Classes:424/480, Cellulose or derivative514/781, Cellulose or derivative514/964SUSTAINED OR DIFFERENTIAL RELEASE TYPEExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)AbstractA carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a controlled and prolonged release pattern upon administration, the carrier base material being a mixture of one or more nonionic cellulose ethers and an anionic surfactant, and wherein at least one of the cellulose ethers is a modified hydroxypropylmethylcellulose having a number average molecular weight of less than 50,000 and has been modified by successive or concurrent exposure to moisture and air.Other References
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