Thieno [3,2-c] pyridine derivatives and their therapeutic application
Patent 4529596 Issued on July 16, 1985. Estimated Expiration Date: 
July 5, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 5, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References2527574 InventorsAssigneeApplicationNo. 06/510582 filed on 07/05/1983US Classes:514/233.8, Plural ring hetero atoms in the bicyclo ring system514/301, Ring sulfur in the bicyclo ring system544/127, The additional six-membered hetero ring is one of the cyclos in a bicyclo ring system544/362, The additional six-membered hetero ring is one of the cyclos in a bicyclo ring system546/114Ring sulfur in the bicyclo ring systemExaminersPrimary: Jiles, Henry R.Assistant: Dentz, Bernard Attorney, Agent or FirmInternational ClassesC07D 495/00 (20060101)C07D 495/04 (20060101) Foreign Application Priority Data1982-07-13 FRAbstractThis invention relates to new thieno [3,2-c] pyridine derivatives having the formula: ##STR1## in which: Y represents the OH group or an OR group in which R is a straight or branched lower alkyl radical, or Y represents a group ##STR2## in which R1 and R2 are each independently of each other, hydrogen or a straight or branched lower alkyl group; or R1 and R2 form together and with the nitrogen atom to which they are attached a heterocycle which may include a second heteroatom such as oxygen or nitrogen, wherein the latter may be substituted by a lower alkyl or benzyl radical which may be substituted; and X represents hydrogen, a halogen or a lower alkyl radical; and their addition salts with pharmaceutically acceptable mineral or organic acids if Y represents the group OR or ##STR3## or with mineral bases if Y represents OH, as well as the two enantiomers or their mixture.The invention also relates to the preparation process of new thieno [3,2-c] pyridine derivatives and to their therapeutic application as blood-platelet aggregation inhibiting agents and antithrombotics. |
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