U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Epimeric azahomoerythromycin A derivative, intermediates and method of use

Patent 4526889 Issued on July 2, 1985. Estimated Expiration Date: Icon_subject April 17, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3478014

3574185

3660376

3674773

3681326

Cis-C3 "C4 "-carbonate derivatives of O-demethyloleandomycin and intermediates therefor
Patent #: 4316010
Issued on: 02/16/1982
Inventor: Nagel

11-Aza-10-deoxo-10-dihydroerythromycin A and derivatives thereof as well as a process for their preparation
Patent #: 4328334
Issued on: 05/04/1982
Inventor: Kobrehel ,   et al.

Novel erythromycin a derivatives
Patent #: 4349545
Issued on: 09/14/1982
Inventor: Gouin d'Ambrieres ,   et al.

4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents Patent #: 4382085
Issued on: 05/03/1983
Inventor: Sciavolino ,   et al.

Inventor

Application

No. 06/601185 filed on 04/17/1984

US Classes:

514/29, The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)536/7.2, Erythromycin or derivative (e.g., oleandomycin, etc.)536/7.4Additional nitrogen containing

Examiners

Primary: Brown, Johnnie R.

Attorney, Agent or Firm

International Classes

C07H 17/00 (20060101)
C07H 17/08 (20060101)

Abstract

Antibacterial 4"-epi-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A, pharmaceutically-acceptable salts thereof, pharmaceutical compositions comprising antibacterially-effective amounts thereof, a method of treatment of bacterial infections with antibacterially effective amounts thereof, and intermediates for the synthesis thereof from erythromycin A.

Other References

  • BNA's "Patent, Trademark & Copyright Journal", vol. 29, 11/84
  • Lullmann et al., "CRC Critical Reviews in Toxicology", 11/75, pp. 185-218
  • Massey et al., Tetrahedron Letters, pp. 157-160, 1970
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