U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treatment for selective weight control

Patent 4525359 Issued on June 25, 1985. Estimated Expiration Date: Icon_subject December 10, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2493471

3074847

3422196

3808317

3818101

Cosmetic compositions having a slimming action Patent #: 4288433
Issued on: 09/08/1981
Inventor: Koulbanis ,   et al.

Inventors

Application

No. 06/448836 filed on 12/10/1982

US Classes:

514/653, Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)514/250, At least three rings in the polycyclo ring system514/263.34, Chalcogen bonded directly to the 2-and 6- positions of the purine ring system (e.g., theophylline, etc.)514/280Pentacyclo ring system having the six-membered hetero ring as one of the cyclos

Examiners

Primary: Robinson, Douglas W.

Attorney, Agent or Firm

International Classes

A61K 47/00 (20060101)
A61K 31/135 (20060101)
A61K 31/41 (20060101)
A61K 31/52 (20060101)
A61K 31/519 (20060101)
A61K 31/48 (20060101)
A61K 31/475 (20060101)

Abstract

A treatment for accelerating regional weight reduction in humans, wherein an active ingredient encouraging elimination of fatty deposits, preferably a beta adrenergic stimulator or an alpha-2 adrenergic inhibitor, is selectively delivered to a regional fat deposit prior to commencing or during a general weight control program, whereby body weight is preferentially reduced in the selected area. The beta adrenergic stimulator, preferably isoproterenol or forskolin, or the alpha-2 adrenergic inhibitor, preferably yohimbine, or combinations thereof may be delivered by any means accomplishing specific delivery to the selected area, including injection, implantation, and topical application to the skin as in an ointment or creme.

Other References

  • Chem. Abst., 80, 30,612(v) (1974)-Jenkins et al
  • The Merck Index, 9th Edition, 1976, 9 pages
  • Goodman & Gilman's, The Pharmacological Basis of Therapeutics, 6th Edition, 1980, Chapter 8, pp. 138 to 154
  • Human Fat Cell Metabolism-Effect of Weight Reduction and Regional Differences, Smith, et al., 22 pages
  • Metabolism, vol. 28, No. 12, (12/79), Regional Differences in the Control of Kipolysis in Human Adipose Tissue, by J. Ostman, et al., pp. 1198 to 1205
  • International Journal of Obesity, 1981, by M. Berlan, et al., Influence of Hypocaloric Diet on-Adrenergic Responsiveness of Obese Human Subcutaneous Adipocytes, pp. 145 to 153
  • Journal of Clinical Endocrinology & Metabolism, vol. 53, No. 5, 1981, by P. Arner, et al., Site Differences in the Basal Metabolism of Subcutaneous Fat in Obese Women, pp. 948 to 952
  • The New England Journal of Medicine, Jul. 1, 1982, H. Motulsky, et al., Adrenergic Receptors in Man, pp. 18 to 29
  • P. Bjorntorp, et al., Human Adipose Tissue Dynamics and Regulation, 1971, pp. 277 to 327
  • European Journal of Clinical Investigation, 1979, M. Lafontan, et al., Alpha-adrenergic Antilipolytic Effect of Adrenaline in Human Fat Cells of the Thigh; Comparison with Adrenaline Responsiveness of Different Fat Deposits, pp. 261-266
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?