U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Composite body for long-term delivery of effective substances

Patent 4525340 Issued on June 25, 1985. Estimated Expiration Date: Icon_subject April 20, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Patent #: 3985298
Issued on: 10/12/1976
Inventor: Nichols

Systems for the controlled release of macromolecules
Patent #: 4164560
Issued on: 08/14/1979
Inventor: Folkman ,   et al.

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Patent #: 4235236
Issued on: 11/25/1980
Inventor: Theeuwes

System with microporous releasing diffusor
Patent #: 4309996
Issued on: 01/12/1982
Inventor: Theeuwes

Method of making prolonged release body
Patent #: 4357312
Issued on: 11/02/1982
Inventor: Hsieh ,   et al.

Systems for the controlled release of macromolecules
Patent #: 4391797
Issued on: 07/05/1983
Inventor: Folkman ,   et al.

Simultaneous delivery of two drugs from unit delivery device
Patent #: 4449983
Issued on: 05/22/1984
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Microporous film with polymer in pores for regulating passage of fluid Patent #: 4450198
Issued on: 05/22/1984
Inventor: Michaels

Inventors

Assignee

Application

No. 06/486846 filed on 04/20/1983

US Classes:

424/424, Membrane or diffusion barrier428/315.5Voids specified as micro

Examiners

Primary: Van Balen, William J.

Attorney, Agent or Firm

International Classes

A01N 25/26 (20060101)
A61K 9/00 (20060101)
A61K 9/20 (20060101)
A61K 9/28 (20060101)

Foreign Application Priority Data

1982-04-21 DE

Abstract

A composite body for long-term delivery of effective substances has a carrier for effective substances composed of a microporous polymer, and a coating composed of cellulose nitrate. The carrier can be composed of a thermoplastic polymer with a substantially isotropic microporous cellular polymer structure with a plurality of substantially spherical cells of a mean diameter between 0.5 and 100 micrometers. The cells are connected with one another by pores. The composite body serves for long-term delivery of peptides, hormones, neurotransmitters, particularly vasopressin and oxytocin.

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