Patent ReferencesControlled release materials and method of use Systems for the controlled release of macromolecules Device for dispensing drug by combined diffusional and osmotic operations System with microporous releasing diffusor Method of making prolonged release body Systems for the controlled release of macromolecules Simultaneous delivery of two drugs from unit delivery device Microporous film with polymer in pores for regulating passage of fluid Patent #: 4450198 InventorsAssigneeApplicationNo. 06/486846 filed on 04/20/1983US Classes:424/424, Membrane or diffusion barrier428/315.5Voids specified as microExaminersPrimary: Van Balen, William J.Attorney, Agent or FirmInternational ClassesA01N 25/26 (20060101)A61K 9/00 (20060101) A61K 9/20 (20060101) A61K 9/28 (20060101) Foreign Application Priority Data1982-04-21 DEAbstractA composite body for long-term delivery of effective substances has a carrier for effective substances composed of a microporous polymer, and a coating composed of cellulose nitrate. The carrier can be composed of a thermoplastic polymer with a substantially isotropic microporous cellular polymer structure with a plurality of substantially spherical cells of a mean diameter between 0.5 and 100 micrometers. The cells are connected with one another by pores. The composite body serves for long-term delivery of peptides, hormones, neurotransmitters, particularly vasopressin and oxytocin. | |