Osmotic device with wall comprising cellulose ether and permeability enhancer

Patent 4519801 Issued on May 28, 1985. Estimated Expiration Date:

July 12, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

2958656

3845770

Antithrombogenic hemo dialysis membranes
Patent #: 4051040
Issued on: 09/27/1977
Inventor: Hazdra , et al.

Micro-porous sheet Patent #: 4171987
Issued on: 10/23/1979
Inventor: Horiguchi , et al.

Inventor

Edgren, David

Assignee

ALZA Corporation

Application

No. 06/397517 filed on 07/12/1982

US Classes:

424/425, Diffusion barrier is matrix424/427, Ocular424/431, Tampon424/436, Anal, rectal (e.g., suppositories, etc.)424/473With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)

Examiners

Primary: Apley, Richard J.
Assistant: Beaucage, Gregory

Attorney, Agent or Firm

International Class

A61K 9/00 (20060101)

Abstract

An osmotic delivery system is disclosed for dispensing a useful agent. The system comprises a semipermeable wall surrounding a compartment housing the agent. The wall comprises a cellulose ether, an organic solvent soluble polymer, and optionally an aqueous soluble polymer. A passageway in the wall connects the interior of the system with the exterior for dispensing an agent from the system.

Other References

Cont. Rel. Tab., Walton et al., Chemical Abstracts, vol. 87, 1977, p. 381, 87:11647p
Folic Acid Animal Feed Materials, Harte et al., Chem. Abs., vol. 89, 1978, p. 409, 89:89136g
Opt. Use of Cell. as Adj. in Mix. with the Aid of Reg. Mode., Moldenhauer et al., Chem. Abs., vol. 89, 1978, p. 361, 89:152646r
Sus. Rel. of Drugs from Et. Cell.-Polyet. Gly. Films and Kin. of Drug Rel., Samuelov et al., Chem. Abs., vol. 90, 1979, p. 390, 90:174620a
Reverse Osmosis w. Dyn. Formed Mem. from Wat. Sol. Poly.; Igawa et al.; J. App. Poly. Sci., vol. 22; 1607-1618; 6/1978
Zero Order Drug del., Donbrow et al., J. Pharm. Phar., 1980, vol. 32, pp. 463-470
Cont. Rel. Tab., Weiss et al., Chem. Abs., vol. 94, 1981, p. 393, 94:214631w