2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
Patent 4515948 Issued on May 7, 1985. Estimated Expiration Date: 
May 7, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 7, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2670351 3692787 InventorsAssigneeApplicationNo. 06/279106 filed on 06/30/1981US Classes:544/325Substituent on 5-position contains carbocyclic ringExaminersPrimary: Hollrah, Glennon H.Assistant: Springer, David B. Attorney, Agent or FirmInternational ClassesC07D 207/327 (20060101)C07D 207/325 (20060101) C07D 207/00 (20060101) C07D 207/32 (20060101) C07D 295/155 (20060101) C07D 239/00 (20060101) C07D 239/48 (20060101) C07D 295/00 (20060101) Foreign Application Priority Data1973-09-12 CHAbstract2,4-Diamino-5-benzylpyrimidines of the formula ##STR1## wherein R1, R2, A, Z and n are as hereinafter set forth, are described. The 2,4-diamino-5-benzylpyrimidines of the invention have useful antibacterial activity. More particularly, they inhibit bacterial dihydrofolate reductase and potentiate the antibacterial activity of sulfonamides.Other References
Field of SearchSubstituent on 5-position contains carbocyclic ring |
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