Resinate of a substituted carboxylic acid, the preparation and use thereof, and pharmaceutical compositions containing it

Patent 4510128 Issued on April 9, 1985. Estimated Expiration Date:

January 6, 2004. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3926864

Cationic hydrogels based on heterocyclic N-vinyl monomers
Patent #: 4058491
Issued on: 11/15/1977
Inventor: Steckler

Novel hypocholesterolemic resin
Patent #: 4198395
Issued on: 04/15/1980
Inventor: De Simone

Methylquinoline high polymer based on quaternary ammonium polymers
Patent #: 4207399
Issued on: 06/10/1980
Inventor: Kambara

Emulsion copolymer cation exchange resins Patent #: 4380590
Issued on: 04/19/1983
Inventor: Chong

Inventor

Khanna, Satish C.

Application

No. 06/568976 filed on 01/06/1984

US Classes:

424/78.16, Amine containing aromatic group514/561, Nitrogen other than as nitro or nitroso nonionically bonded521/32, Treated with nitrogen-containing material525/332.2Divinyl benzene

Examiners

Primary: Schofer, Joseph L.
Assistant: Lipman, Bernard

Attorney, Agent or Firm

Glynn; Michael W.

International Classes

A61K 31/785 (20060101)
A61K 31/74 (20060101)
A61K 47/48 (20060101)
A61K 31/185 (20060101)
A61K 31/195 (20060101)
C08F 8/44 (20060101)
C08F 8/00 (20060101)

Foreign Application Priority Data

1983-01-12 CH

Abstract

A resinate of the formula ##STR1## wherein Am⊕ is a strongly basic copolymer of styrene and divinylbenzene which is in cationic form, said copolymer containing the sum of m+n quaternary ammonium groups and also containing, as main structural unit, the grouping of the formula ##STR2## X⦵ is the anion of an acid different from the anion of the formula ##STR3## and m and n denote the entire ion capacity of the copolymer, and the molecular weight of which is about 107 to 109, a process for the preparation of said resinate, the use thereof as active ingredient of a drug, and pharmaceutical compositions containing it.

Other References

Chemical Abstracts-141851d, "Antiinflammatory Action of N-(2,6-dichlorophenyl)-O-aminophenylacetic Acid . . . " 1973, Tsurumi et al
C.A.-16108w, "Structure-Activity Relationships in a Series of Antiinflammatory N-arylantranilic Acids," Kultenbronn et al., 1983