Patent References 2928846 3184456 3398151 3717634 3850922 3907801 Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones Buspirone anti-anxiety method Patent #: 4182763 InventorsAssigneeApplicationNo. 06/446047 filed on 12/01/1982US Classes:514/252.19, Five-membered nitrogen hetero ring attached directly or indirectly to the 1,3-diazine ring by nonionic bonding514/253.09, Five-membered nitrogen hetero ring attached directly or indirectly to the piperazine ring by nonionic bonding514/254.01, The additional hetero ring is five-membered having ring nitrogen544/230, Spiro544/295, Plural diazine rings544/364, At least three hetero rings containing544/372Five-membered hetero ring consisting of one nitrogen and four carbonsExaminersPrimary: Hollrah, Glennon H.Assistant: Turnipseed, James H. Attorney, Agent or FirmInternational ClassesC07D 209/00 (20060101)C07D 403/12 (20060101) C07D 209/76 (20060101) C07D 401/00 (20060101) C07D 403/00 (20060101) C07D 401/12 (20060101) C07D 491/18 (20060101) C07D 491/00 (20060101) Foreign Application Priority Data1981-12-22 JPAbstractSuccinimide derivatives representable by the following formula: ##STR1## wherein X and Y are combined to form a group of the formula: ##STR2## (wherein A is an oxygen atom, a methylene group or an ethylene group and a full line accompanying a broken line ( ) is a single bond or a double bond) and Z is a hydrogen atom or, X and Z are combined to form a group of the formula: ##STR3## (wherein A and a full line are each as defined above) and Y is a hydrogen atom, R is a phenyl group, optionally substituted with halogen, C1 -C4 alkyl, C1 -C4 alkoxy or trifluoromethyl, a 2-pyridyl group or a 2-pyrimidinyl group and n is an integer of 3 or 4, and pharmaceutically acceptable acid addition salts thereof, which are useful as antianxious substances.Other References
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