U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Inclusion compound of lankacidin-group antibiotic and use thereof

Patent 4497803 Issued on February 5, 1985. Estimated Expiration Date: Icon_subject April 6, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2959580

3869443

Nitroglycerine inclusion compounds with cyclodextrin and composition containing same
Patent #: 4073931
Issued on: 02/14/1978
Inventor: Akito ,   et al.

Inclusion complex of cyclodextrin and indomethacin and a process for the preparation thereof, method of use and pharmaceutical composition
Patent #: 4228160
Issued on: 10/14/1980
Inventor: Szejtli ,   et al.

Inclusion compound of p-hexadecylamino benzoic acid in cyclodextrin and method of use Patent #: 4407795
Issued on: 10/04/1983
Inventor: Nicolau ,   et al.

Inventors

Assignee

Application

No. 06/482553 filed on 04/06/1983

US Classes:

514/450, The hetero ring has at least seven members514/546, ZC(=O)OY, wherein Z is an acyclic radical bonded to the C=O by a carbon and Y is an organic radical bonded to the oxygen by a carbon536/103, Dextrin or derivative536/7.1Oxygen containing hetero ring having 12-19 members (e.g., methymycin, carbomycin, spiramycin, etc.)

Examiners

Primary: Brown, Johnnie R.
Assistant: Peselev, Elli

Attorney, Agent or Firm

International Classes

A61K 47/48 (20060101)
C07D 493/00 (20060101)
C07D 493/08 (20060101)
C08B 37/00 (20060101)

Foreign Application Priority Data

1982-04-12 JP

Abstract

Inclusion compound of lankacidin-group antibiotic with cyclodextrin, having enhanced water-solubility and stability and a veterinary composition containing the same, which is useful for curing swine dysentery. The compound is prepared by adding lankacidin-group antibiotic to an aqueous cyclodextrin solution and stirring.

Other References

  • Tsuchiya et al., The Journal of Antibiotics, vol. 24, pp. 29-41, (1971)
  • The Merck Index, p. 755, No. 5104
  • The Merck Index, p. 893, No. 6100
  • Kinashi et al., Tetrahedron Letters, vol. 22, No. 39, pp. 3861-3864
  • S. Harada et al., The Journal of Antibiotics, 26, 647-657, (1973)
  • Central Patent Index; Basic Abstract Journal Section B: 21094 E/11, (Week E11, May 12, 1982)
  • W. Saenger, Angewandte Chemie International Edition in English, 19; 344-362, (1980)
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