Pharmaceutical compositions and methods for producing alpha antagonism
Patent 4496558 Issued on January 29, 1985. Estimated Expiration Date: 
January 26, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 26, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2520264 3716639 3752892 3795683 3906006 Intermediates in the preparation of 2,3,4,5-tetrahydro-1H-3-benzazepines Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines Substituted 1,2,4,5-tetrahydro-3H, 3 benzazepines 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines Patent #: 4265890 InventorsAssigneeApplicationNo. 06/461058 filed on 01/26/1983US Classes:514/217.013-Benzazepines (including hydrogenated)ExaminersPrimary: Robinson, Douglas W.Attorney, Agent or FirmInternational ClassesC07D 223/00 (20060101)C07D 223/16 (20060101) AbstractPharmaceutical compositions and methods for producing alpha2 antagonism utilize, as active ingredients, 6-halo-N-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines. These compositions are particularly useful for lowering intraocular pressure and for the treatment of abnormal cardiovascular conditions such as, for example, congestive heart failure, angina pectoris and thrombosis. The compositions and compounds of this invention, also, produce a reduction in blood pressure in hypertensive subjects and are, therefore, useful as antihypertensive agents.Other References
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