Antiplaque dentifrice with improved fluoride stability
July 13, 2003. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3927201 Method of making dentifrice compositions containing insolubilized salts of 1,6-di-(p-chlorophenyl biguanido) hexane Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies Oral preparations Insolubilized salts of 1,6-di-p-(chlorophenyl biguanido) hexane Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents Toothpaste containing milled alpha-alumina trihydrate Toothpaste compositions Oral compositions containing bis-biguanides with reduced staining tendencies Anti-caries preparations InventorsApplicationNo. 06/513474 filed on 07/13/1983US Classes:424/52, Fluorine or fluorine compound containing424/49, DENTIFRICES (INCLUDES MOUTH WASH)424/54, Ammonia, amine, or derivative thereof (e.g., urea, etc.)424/57Phosphate compound containingExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 8/41 (20060101)A61K 8/44 (20060101) A61K 8/30 (20060101) A61Q 11/00 (20060101) AbstractA stable antiplaque dentifrice with improved foaming and improved fluoride stability containing an antiplaque quaternary ammonium compound, a betaine surfactant to improve foaming without inactivating the anti-bacterial and antiplaque activity of the quaternary ammonium compound, a humectant selected from the group consisting of polyethylene glycol, sorbitol, and mixtures thereof, a nonionic gelling agent, preferably hydroxyethylcellulose and a fluorine-containing compound capable of providing a fluoride ion, a small amount of glycerin to improve fluoride stability in polyethylene glycol humectant, in an aqueous vehicle containing a dental abrasive. A small amount of glycerin, as low as 1%, improves the long term fluoride stability of the dentifrice without adversely affecting the cosmetic stability thereof.Field of SearchDENTIFRICES (INCLUDES MOUTH WASH)Ferment containing (e.g., enzymes, bacteria, etc.) Iodine or iodine compound containing Fluorine or fluorine compound containing Oxygen or chlorine releasing compound containing Ammonia, amine, or derivative thereof (e.g., urea, etc.) Hydroxy carboxylic acid or derivative thereof (e.g., methyl salicylate, etc.) Organic sulfate or sulfonate containing Phosphate compound containing Plant extract of undetermined constitution | |
