Inclusion compounds of cyclodextrin with sulfur-containing compounds
September 30, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 435618 3246025 Azetidine-2-carboxylic acid derivatives Compounds and method for alleviating angiotensin related hypertension Cysteine derivatives Method for treating rheumatism Antihypertensive amides Antihypertensive 5-substituted 2-pyrrolidinecarboxylic acids Cysteine derivatives Disulfide compounds Patent #: 4347371 InventorsAssigneeApplicationNo. 06/432929 filed on 09/30/1982US Classes:536/46, Dextrin derivatives514/855ExpectorantExaminersPrimary: Brown, Johnnie R.Assistant: Peselev, Elli Attorney, Agent or FirmInternational ClassesA61K 47/48 (20060101)C07D 207/00 (20060101) C07D 207/16 (20060101) C07D 277/00 (20060101) C07D 277/06 (20060101) C08B 37/00 (20060101) Foreign Application Priority Data1981-02-28 JPAbstractThis invention relates to inclusion compounds of cyclodextrin with the compounds of the general formula [I] and salts thereof, which show pharmacological effects (for example antihypertensive effect), ##STR1## wherein A is straight or branched lower alkylene;R1 is hydrogen or lower alkyl;R2 is hydrogen, lower alkyl, phenyl, phenyl-lower alkyl, hydroxyphenyl-lower alkyl, hydroxy-lower alkyl, amino-lower alkyl, guanidino-lower alkyl, imidazolyl-lower alkyl, indolyl-lower alkyl, mercapto-lower alkyl or lower alkylthio-lower alkyl;R1 or R2 may join to complete pyrrolidine ring or thiazolidine ring, and each ring may be substituted by phenyl or pyridyl, and phenyl may be resubstituted by hydroxy, lower alkoxy, halogen, nitro or sulfamoyl;R3 is hydrogen or ##STR2## said lower alkyl and lower alkoxy having 1 to 6 carbon atoms.Other References
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