U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor

Patent 4474768 Issued on October 2, 1984. Estimated Expiration Date: Icon_subject November 15, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3928387

Semi-synthetic oleandomycin derivatives - C8 modifications
Patent #: 4110531
Issued on: 08/29/1978
Inventor: Sciavolino

Erythromycylamine 11,12-carbonate and derivatives thereof
Patent #: 4283527
Issued on: 08/11/1981
Inventor: Sciavolino

11-Aza-10-deoxo-10-dihydroerythromycin A and derivatives thereof as well as a process for their preparation Patent #: 4328334
Issued on: 05/04/1982
Inventor: Kobrehel ,   et al.

Inventor

Application

No. 06/441981 filed on 11/15/1982

US Classes:

514/29, The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)536/7.4Additional nitrogen containing

Examiners

Primary: Brown, Johnnie R.
Assistant: Peselev, Elli

Attorney, Agent or Firm

International Class

C07H 17/00 (20060101)

Abstract

Antibacterial N-methyl 11-aza-10-deoxo-10-dihydroerythromycin A and pharmaceutically acceptable acid addition salts thereof, intermediates therefor, and processes for their preparation.

Other References

  • Migridichian Organic Synthesis, vol. 1, New York: Reinhold Pub. Corp. 1957, p. 476
  • Greene, "Protective Groups in Organic Synthesis", John Wiley & Sons, Inc., N.Y., 1981, p. 281
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