Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives
Patent 4469797 Issued on September 4, 1984. Estimated Expiration Date: 
September 23, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 23, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3855208 Derivatives of digoxigenin Chemical process Patent #: 4082747 InventorAssigneeApplicationNo. 06/422217 filed on 09/23/1982US Classes:436/536, INVOLVING IMMUNE COMPLEX FORMED IN LIQUID PHASE435/28, Involving peroxidase435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/7.7, Assay in which a label present is an apoenzyme, prosthetic group, or enzyme cofactor435/7.93, Competitive assay436/537, Signal modification or steric inhibition436/544, Producing labeled antigens436/546, Fluorescent label436/800, FLUORESCENT DYES (E.G., RHODAMINE, ETC.)436/817, Steroids or hormones530/363, Serum albumin, e.g., BSA, HSA, etc.530/389.8, Binds drug, hapten, hapten-carrier complex, or specifically-identified chemical structure (e.g., theophylline, digoxin, etc.)530/405, Nitrogen containing reactant530/806, ANTIGENIC PEPTIDES OR PROTEINS540/104Nitrogen or sulfur attached directly or indirectly to the cyclopentanohydrophenanthrene ring system by nonionic bondingExaminersPrimary: Nucker, Christine M.Attorney, Agent or FirmInternational ClassesG01N 33/94 (20060101)C07J 41/00 (20060101) G01N 33/531 (20060101) AbstractImmunogen conjugates comprising N-substituted-amino-3-desoxydigoxigenin derivatives coupled to conventional immunogenic carrier materials, and antibodies raised against such conjugates. Also provided are labeled digoxigenin conjugates for use with the digoxigenin antibodies in preferred immunoassay techniques for determining digoxin in biological fluids.Other References
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