U.S. patents available from 1976 to present.
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Vaccinal complex containing a specific antigen and vaccine containing it

Patent 4460575 Issued on July 17, 1984. Estimated Expiration Date: Icon_subject July 17, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3725545

Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid
Patent #: 3952097
Issued on: 04/20/1976
Inventor: Levy

Antigens comprising immunostimulant adjuvants and their use in immunotherapy Patent #: 4285930
Issued on: 08/25/1981
Inventor: Likhite

Inventors

Assignee

Application

No. 06/236534 filed on 02/20/1981

US Classes:

424/197.11, Conjugate or complex includes bacterium or component thereof or substance produced by said bacterium424/234.1, Bacterium or component thereof or substance produced by said bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, etc.)424/243.1, Staphylococcus (e.g., Staphylococcus aureus, etc.)424/244.1, Streptococcus (e.g., Group B Streptococcus, pneumococcus or Streptococcus pneumoniae, etc.)424/245.1, Corynebacterium (e.g., Corynebacterium diphtheriae, etc.)424/248.1, Mycobacterium (e.g., Mycobacterium tuberculosis, Calmette-Guerin bacillus (i.e., BCG), etc.)424/250.1, Neisseria meningitidis424/256.1, Hemophilus (e.g., Hemophilus influenzae, Hemophilus gallinarum, Hemophilus pleuropnemoniae, etc.)424/257.1, Escherichia (e.g., Escherichia coli, etc.)424/258.1, Salmonella (e.g., Salmonella typhimurium, etc.)424/259.1, Klebsiella (e.g., Klebsiella pneumoniae, etc.)424/831, INVOLVING CAPSULAR POLYSACCHARIDE OF BACTERIUM (E.G., POLYRIBOSYL RIBITOL PHOSPHATE (PRP), ETC.)530/405, Nitrogen containing reactant530/807, HAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN536/23.1, DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)536/24.2Non-coding sequences having no known regulatory function which are adaptors or linkers for vector or gene contruction

Examiners

Primary: Hazel, Blondel

Attorney, Agent or Firm

International Class

A61K 39/39 (20060101)

Foreign Application Priority Data

1980-02-20 FR

Abstract

The present invention relates to a vaccinal complex containing a specific antigen. This is a vaccinal complex characterized in that it is composed of bacterial ribosomal RNA or fragments of bacterial ribosomal RNA on which are coupled from 1 to 5% by weight of a specific antigen of bacterial serotype. This complex may be used as a vaccine.

Other References

  • Chemical Abstracts, vol. 87, p. 376, Abst. No. 11603w, 1977
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