Osmotic device for dispensing two different medications

Patent 4455143 Issued on June 19, 1984. Estimated Expiration Date:

March 22, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3845770

3916899

Osmotic system for the controlled and delivery of agent over time
Patent #: 4111202
Issued on: 09/05/1978
Inventor: Theeuwes

Osmotic device with compartment for governing concentration of agent dispensed from device
Patent #: 4210139
Issued on: 07/01/1980
Inventor: Higuchi

System for delivering agent at zero order rate with emerging agent below saturation Patent #: 4298003
Issued on: 11/03/1981
Inventor: Theeuwes , et al.

Inventors

Assignee

ALZA Corporation

Application

No. 06/360396 filed on 03/22/1982

US Classes:

604/892.1Osmotic or diffusion pumped device or system

Examiners

Primary: Padgett, Benjamin R.
Assistant: Wallen, T. J.

Attorney, Agent or Firm

International Class

A61K 9/00 (20060101)

Abstract

An osmotic device is disclosed for delivering two beneficial drugs to an environment of use. The device comprises a semipermeable wall surrounding a lumen divided into a first compartment containing a drug that is separated from a second compartment containing a different drug. An orifice through the wall communicates with the first compartment for delivering drug from the first compartment, and another orifice through the wall communicates with the second compartment for delivering drug from the second compartment. In operation, drug is dispensed separately from each compartment by fluid being imbibed through the wall into each compartment at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall against the drug in each compartment thereby producing in each compartment a solution containing drug that is dispensed through their orifices at a controlled and continuous rate over a prolonged period of time.