Patent References 3846476 3852338 Process and composition for decreasing blood serum prolactin levels Patent #: 4224343 InventorApplicationNo. 06/407960 filed on 08/13/1982US Classes:514/280, Pentacyclo ring system having the six-membered hetero ring as one of the cyclos514/215, Additional hetero atom in the polycyclo ring system514/288, Ring carbon is shared by three of the cyclos514/324, Ring sulfur in the polycyclo ring system514/325, Polycyclo ring system is tricyclo-carbocyclic514/326, The additional ring is a hetero ring514/419, C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen)514/654The chain consists of two or more carbons which are unsubtituted or have acyclic hydrocarbyl substituents onlyExaminersPrimary: Schwartz, Richard A.Attorney, Agent or FirmInternational ClassesA61K 45/06 (20060101)A61K 45/00 (20060101) A61K 31/475 (20060101) A61K 31/495 (20060101) AbstractA method of improving the arteriosclerotic condition in an animal having arteriosclerosis or having a high risk of developing arteriosclerosis, which method comprises administering an effective amount of a serotonin regulating agent, to inhibit the biological activity of serotonin within the blood vessels, thereby inhibiting the proliferation of smooth muscle cells, which has been found to cause or contribute to an arteriosclerotic condition.Other References
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