Monoclonal antibody
June 21, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod of producing antibodies Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers Tumor localization and therapy with labeled anti-CEA antibody Complement-fixing monoclonal antibody to human T cells, and methods of preparing same Complement-fixing monoclonal antibody to human suppressor T cells and methods of preparing same Monoclonal antibody to human T cells, and methods for preparing same Monoclonal antibody to human cytotoxic and suppressor T cells and methods of preparing same Monoclonal antibody to a human thymocyte antigen and methods of preparing same Monoclonal antibody to a human prothymocyte antigen and methods of preparing same Monoclonal antibody to a human monocyte antigen and methods of preparing same InventorsAssigneeApplicationNo. 06/390548 filed on 06/21/1982US Classes:530/388.75, Binds T-lymphocytic cell or component or product thereof (e.g., T cell, thymocyte, T-lineage bone marrow cell, T-lymphoblastoid cell, T-lineage acute lymphoblastic leukemia cell, T-lymphocytic cell-surface antigen, etc.)424/154.1, T lymphocytic cell (e.g., T cell, thymocyte, etc.)424/178.1, CONJUGATE OR COMPLEX OF MONOCLONAL OR POLYCLONAL ANTIBODY, IMMUNOGLOBULIN, OR FRAGMENT THEREOF WITH NONIMMUNOGLOBULIN MATERIAL424/183.1, Conjugated to proteinaceous toxin or fragment thereof (e.g., conjugated to diphtheria toxin, Pseudomonas exotoxin, ricin, gelonin, abrin, etc.)435/7.24, Leukocyte (e.g., lymphocyte, granulocyte, monocyte, etc.)435/70.21, Producing monoclonal antibody436/548, Monoclonal antibody530/391.3, Conjugated to a detectable label or radioisotope or radionuclide or heavy metal-containing compound530/391.7, Conjugated to a cytotoxic agent, drug, or other biologically-active substance530/864, Monoclonal530/868, INVOLVING AUTOIMMUNITY, ALLERGY, IMMEDIATE HYPERSENSITIVITY, DELAYED HYPERSENSITIVITY, IMMUNOSUPPRESSION, OR IMMUNOTOLERANCE600/3Radioactive substance placed within body (e.g., inhaled, implanted, injected, etc.)ExaminersPrimary: Padgett, Benjamin R.Assistant: Moskowitz, M. International ClassesA61K 47/48 (20060101)C07K 16/18 (20060101) C07K 16/28 (20060101) G01N 33/564 (20060101) A61K 38/00 (20060101) AbstractMonoclonal antibodies specific to a mature human T cell surface antigen of molecular weight of about 120,000 daltons as determined by electrophoresis, the antigen not being modulated by monoclonal antibodies specific to it and being restricted within the human lymphoid system to the surface of mature T cells, the monoclonal antibodies being capable of selectively binding mature human T cells and rendering them inactive in vivo and failing to induce the proliferation or activation of human lymphocytes.Other References
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