U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Water and drug delivery system for suppository use

Patent 4439194 Issued on March 27, 1984. Estimated Expiration Date: Icon_subject September 8, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

1573976

1812769

2110962

3490454

3521637

3845770

Drug delivery device
Patent #: 3967618
Issued on: 07/06/1976
Inventor: Zaffaroni

Osmotic device having microporous reservoir
Patent #: 3977404
Issued on: 08/31/1976
Inventor: Theeuwes

Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina Patent #: 4160452
Issued on: 07/10/1979
Inventor: Theeuwes

Inventors

Assignee

Application

No. 06/300370 filed on 09/08/1981

US Classes:

424/436Anal, rectal (e.g., suppositories, etc.)

Examiners

Primary: Rosenbaum, C. Fred
Assistant: Wallen, T. J.

Attorney, Agent or Firm

International Classes

A61K 9/02 (20060101)
A61M 31/00 (20060101)

Abstract

A drug delivery system designed to deliver water and drug to the site of administration is composed of a core of an aqueous solubulizing system in a wax housing, which melts at body temperature, surrounded by a matrix of drug and water-dispersible excipients. The entire unit may also be coated with a semi-permeable membrane to modulate drug release.

Other References

  • Australian Journal of Experimental Biology, vol. 33, pp. 415-420 (1955), "A Continuous Long-Term Injector"
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