Patent References 1573976 1812769 2110962 3490454 3521637 3845770 Drug delivery device Osmotic device having microporous reservoir Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina Patent #: 4160452 InventorsAssigneeApplicationNo. 06/300370 filed on 09/08/1981US Classes:424/436Anal, rectal (e.g., suppositories, etc.)ExaminersPrimary: Rosenbaum, C. FredAssistant: Wallen, T. J. Attorney, Agent or FirmInternational ClassesA61K 9/02 (20060101)A61M 31/00 (20060101) AbstractA drug delivery system designed to deliver water and drug to the site of administration is composed of a core of an aqueous solubulizing system in a wax housing, which melts at body temperature, surrounded by a matrix of drug and water-dispersible excipients. The entire unit may also be coated with a semi-permeable membrane to modulate drug release.Other References
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