U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Platinum(IV)-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum(IV)-diamine complex for the treatment of malignant tumors in mice

Patent 4431666 Issued on February 14, 1984. Estimated Expiration Date: Icon_subject February 14, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of treating viral infections
Patent #: 4053587
Issued on: 10/11/1977
Inventor: Davidson ,   et al.

Compositions containing platinum
Patent #: 4119654
Issued on: 10/10/1978
Inventor: Tobe ,   et al.

Malonato platinum anti-tumor compounds
Patent #: 4140707
Issued on: 02/20/1979
Inventor: Cleare ,   et al.

Compositions containing platinum
Patent #: 4228090
Issued on: 10/14/1980
Inventor: Hydes ,   et al.

Compositions containing platinum Patent #: 4250189
Issued on: 02/10/1981
Inventor: Hydes ,   et al.

Inventors

Assignee

Application

No. 06/232298 filed on 02/06/1981

US Classes:

514/492, Heavy metal containing DOAI556/137, Nitrogen bonded directly to the metal987/11Devoid of any platinum atom directly bonded to carbon (15/00N7B)

Examiners

Primary: Sneed, Helen M. S.

Attorney, Agent or Firm

International Class

C07F 15/00 (20060101)

Foreign Application Priority Data

1980-03-01 NL

Abstract

Platinum(IV)-diamine-complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum(IV)-diamine-complex for the treatment of malignant tumors in mice as well as the shaped medicine thus obtained.This invention relates to novel platinum-diamine complexes, a pharmaceutical composition using the novel complexes and methods of treating malignant tumors in mice using the pharmaceutical composition.

Other References

  • Braddock et al., Chemico-Biological Interactions, vol. 11, No. 3, pp. 158-159 (1975)
  • Van Kralingen, C. G., Antitumor Platinum Compounds; Synthesis, Structure and Biological Activity, No. 7, 1979
  • B. Rosenberg and L. Van Camp, Cancer Research 30 (1970) 1799-1802
  • A. P. Zipp and S. G. Zipp, J. Chem. Ed., 54 (12) (1977) p. 739
  • M. L. Tobe and A. R. Khokhar, J. Clinical Hematol. Oncol., 7 (1) (1977), pp. 114-134
  • Appleton, T. C. and Hall, J. R., Inorganic Chemistry, vol. 11, No. 1, 1972, pp. 112-117
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