Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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US Patent 4427651 - Enriched plasma derivative for enhancement of wound closure and coverage
US Patent Issued on January 24, 1984
Estimated Patent Expiration Date:
June 7, 2002Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
June 7, 2002Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA sprayable preparation for accelerated hemostasis and optimized biochemical control of wound closure contains a powdery mixture of 15 to 60% by weight of thrombin, 5 to 80% by weight of a desiccating and stabilizing agent, viz., albumin, globulin and/or fibrinogen, and 1 to 10% by weight of a fibrinolysis inhibitor. The powdery mixture is suspended in a low-boiling, anhydrous solvent, which is used as a propellant. For effective wound closure and coverage, a spray jet of this suspension is directed onto the wound under evaporation of the solvent so that substantially only the dry, solid powdery mixture reaches the wound. This method of application by spraying is also disclosed.Other References
| InventorAssigneeApplicationNo. 06/385665 filed on 06/07/1982US Classes:424/46, Powder or dust containing424/45, Organic pressurized fluid424/531, Serum424/532, Platelet514/21, Produced by or extracted from animal tissue514/802, FIBRINOPEPTIDES, BLOOD-COAGULATION FACTORS OR DERIVATIVES530/363, Serum albumin, e.g., BSA, HSA, etc.530/381, Blood coagulation factors and fibrin, e.g., thromboplastin, etc.530/382, Fibrin or fibrin intermediates, e.g., fibrinogen, etc.530/383, Blood coagulation factor VIII, AHF530/384, Blood coagulation factor II or factor II + VII + IX + X, i.e., prothrombin complex or factor530/386, Globulins530/830Plasma; serumField of Search424/46, Powder or dust containing424/45Organic pressurized fluidExaminersPrimary: Rosen, SamAttorney, Agent or FirmUS Patent References4298598, Tissue adhesiveIssued on: 11/03/1981 Inventor: Schwarz , et al.4362567Tissue adhesive Issued on: 12/07/1982 Inventor: Schwarz , et al. International ClassesA61K 35/14 (20060101)A61K 38/00 (20060101) A61K 38/43 (20060101) A61K 38/48 (20060101) A61K 38/36 (20060101) A61L 27/00 (20060101) A61L 24/00 (20060101) A61L 24/10 (20060101) A61L 26/00 (20060101) A61L 27/22 (20060101) A61F 2/00 (20060101) Foreign Application Priority Data1981-06-25 DE |
