Patent ReferencesRetard form of pharmaceuticals with insoluble porous diffusion coatings Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof Patent #: 4367217 InventorsAssigneeApplicationNo. 06/389282 filed on 06/17/1982US Classes:424/459, Organic coatings424/475, Organic coatings424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/494, Cellulose derivatives514/262.1Exactly four ring nitrogens in the bicyclo ring systemExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmInternational ClassesA61K 9/16 (20060101)A61K 9/20 (20060101) A61K 9/50 (20060101) A61K 31/505 (20060101) Foreign Application Priority Data1981-06-19 DEAbstractThis invention relates to vehicles for the administration of dipyridamole. More specifically, this invention relates to a method of treating cardiovascular disorders in a host in need of such treatment which comprises administering to said host a cardiovascularly effective amount of a composition comprised of (i) dipyridamole or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 5 acid equivalents to 1 mol of dipyridamole, preferably in the form of particles having particle sizes of from about 0.1 to 2.0 mm. | |