Process for selective separation of molecular species from mixtures thereof using cyclodextrins

Patent 4426292 Issued on January 17, 1984. Estimated Expiration Date:

February 19, 2002. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3472835

Inventors

Application

No. 06/350194 filed on 02/19/1982

US Classes:

210/635, Liquid/liquid or gel type (i.e., jellylike) chromatography210/502.1, Sorptive component containing95/104, Sweep gas used95/106, With heating or cooling95/127, Noble gas sorbed95/144, Alkene sorbed95/147Benzene ring containing compound sorbed

Examiners

Primary: Adee, John

Attorney, Agent or Firm

Hasak; Janet E.

International Classes

C10G 25/00 (20060101)
B01D 53/02 (20060101)
B01D 15/08 (20060101)
C08B 37/00 (20060101)
C08B 37/16 (20060101)
G01N 30/00 (20060101)

Abstract

A mixture of two or more fluid molecular species is resolved into its compartment parts by a selective separation process whereby the mixture is contacted with a solid particulate monomeric cyclodextrin. On contact, at least one of the molecular species is selectively sorbed onto the cyclodextrin, and thereafter the species is desorbed from the cyclodextrin. In a preferred aspect, the species to be separated are organic compounds.

Other References

Chromatographic and Allied Methods by Mikes, John Wiley and Sons of New York, pp. 335-343 and 368 relied on, 1979
E. Smolkova et al., J. Chromatography, 241, 3 (1982)
E. Smolkova-Keulemansova, J. Chromatography, 251, 17 (1982)
M. Benito Casu et al., Carbohydrate Research, 76, 59 (1979)
Y. Mizobuchi, et al., J. Chromatogr., 208, 35 (1981)
J. Szejtli, Staerke, 30, 127 (1978)
B. Siegel et al., J.A.C.S., 97, 6869 (1975)
H. Schlenk et al., J.A.C.S., 83, 2312 (1961)
G. Phillips et al., J. Chem. Soc., 387, (1966)
J. Szejtli et al., Acta Chim. Acad. Sci., Hung., 101, 27 (1979)
J. Szejtli et al., Acta Chim. Acad. Sci., Hung., 94, 383 (1977)
M. Maciejewski et al., J. Macromol. Sci. Chem., A13, 87 (1979)
D. French, PhD Thesis, Iowa State Univ. (1942)
H. Schlenk et al., J.A.C.S., 77, 3587 (1955)
CPC International Product Brochure "Beta-Cyclodixtrin", Englewood Cliffs, N.J. (1968)
T. Kuge et al., Agr. Biol. Chem., 32, 753 (1968)
C. Lee, Sepn. Sci. Technol., 16, 25 (1981)
C. Lee, J. Appl. Polym. Sci., 26, 489 (1981)
D. Sand et al., Anal. Chem., 33, 1624 (1961)
H. Schlenk et al., Anal. Chem., 34, 1529 (1962)
Y. Mizobuchi et al., Bull. Chem. Soc. Jpn., 54, 2487 (1981)
Y. Mizobuchi et al., J. Chromatogr., 194, 153 (1980)
M. Tanaka et al., J. Chromatogr., 219, 108 (1981)
F. R. Senti et al., in L. Mandelcorn, Ed., "Non Stoichiometric Compounds", Academic Press, N.Y., 1964, pp. 568-605
D. W. Griffiths et al., Advances in Catalysts, 23, 209 (1973)
J. A. Thoma et al., in R. L. Whistler et al., Ed., "Starch: Chemistry and Technology", vol. I, Academic Press, N.Y., 1965, pp. 209-249
D. French, Advan. Carbohydrate Chem., 12, 189 (1957)
M. L. Bender et al., "Cyclodextrin Chemistry", Springer-Verlag, N.Y., 1978
W. Saenger, Angew. Chem. Int. Ed., Engl., 19, 344 (1980)
W. Saenger, in B. Pullman, Ed., "Environmental Effects on Molecular Structure and Properties", Reidel, Dordrecht, Holland, 1976, pp. 265-305
D. W. Breck, "Zeolite Molecular Sieves: Structure, Chemistry, and Use", Wiley, New York, 1974, p. 609
B. Klar et al., Acta Cryst., B36, 1154 (1980)