Electrochemical flow cell, particularly use with liquid chromatography

Patent 4413505 Issued on November 8, 1983. Estimated Expiration Date:

March 9, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3649498

3676321

3694335

Conductivity measurement probe
Patent #: 3936729
Issued on: 02/03/1976
Inventor: Winslow, Jr.

Measuring cells for measuring electrical conductivity of liquids Patent #: 3993945
Issued on: 11/23/1976
Inventor: Warmoth , et al.

Inventor

Matson, Wayne R.

Assignee

Environmental Sciences Associates, Inc.

Application

No. 06/241945 filed on 03/09/1981

US Classes:

73/61.55, Including sampling, sample handling, or sample preparation204/411Three or more electrodes

Examiners

Primary: Kazenske, E. R.
Assistant: Roskos, Joseph W.

Attorney, Agent or Firm

Hayes, Davis & Soloway

International Classes

G01N 30/34 (20060101)
G01N 27/49 (20060101)
G01N 30/00 (20060101)
G01N 30/14 (20060101)
G01N 30/64 (20060101)
G01N 30/02 (20060101)

Abstract

An amperometric cell modified for high pressure operation is described. The cell is a flow-through type cell defining a flow path and has at least one active testing electrode, at least one reference electrode and at least one counter electrode operatively disposed and electrically insulated from one another within the cell flow path. In a preferred embodiment the flow cell is encapsulated within a high impact, chemically resistant, chemically insulating material, and has a pair of high pressure resistance fittings communicating with the flow path and extending in part beyond the encapsulation. The cell has particular utility for use with a liquid chromatography separation and when placed in line upstream of sample injection, will remove selected electroactive components in the carrier fluid and thereby reduce background level of contaminents reaching the column and eluting from the column. The cell may also be placed in line following sample injection whereby it may be employed to electrochemically modify selected materials in the mobile phase whereby to change their chromatographic characteristics.