InventorsApplicationNo. 06/422891 filed on 09/24/1982US Classes:514/29, The hetero ring has exactly 13 ring carbons (e.g., erythromycin, etc.)514/152, 3,10-dihydroxy-2-naphthacene carboxamide or derivative (e.g., tetracycline, etc.) DOAI514/179, Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)514/274, Chalcogen bonded directly to pyrimidine at 2-position514/652, Alkanol group only between the amino nitrogen and an ether oxygen which is bonded directly to the aryl ring or aryl ring system (i.e., aryloxy alkanol amines)514/714, Peroxide DOAI514/788, Nitrogen containing514/947, Topical application514/975CHARACTERIZED BY THE DESIGNATED SURFACTANT USEDExaminersPrimary: Rosen, SamAttorney, Agent or FirmInternational ClassesA61K 47/18 (20060101)A61K 47/22 (20060101) A61K 47/16 (20060101) AbstractTopical therapeutic compositions are disclosed which contain from about 0.1 to 70 percent by weight of a water-soluble tertiary amine oxide and a therapeutic agent selected from the group consisting of erythromycin, benzoyl peroxide, hydrocortisone, tetracycline, 5-fluorouracil, and propranolol. The amine oxide enhances penetration of the therapeutic agent into and through the skin.Other References
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