U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Electrochemical detection system and method of analysis

Patent 4404065 Issued on September 13, 1983. Estimated Expiration Date: Icon_subject September 13, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inventor

Assignee

Application

No. 06/111917 filed on 01/14/1980

US Classes:

205/780.5, For nitrogen or nitrogen containing compound204/411, Three or more electrodes205/792.5, Using ion exchange resin210/198.2, Chromatography210/656, Chromatography422/70, Liquid chromatography436/161, INCLUDING CHROMATOGRAPHY73/61.58Detector detail

Examiners

Primary: Kaplan, G. L.

Attorney, Agent or Firm

International Classes

G01N 33/68 (20060101)
G01N 27/403 (20060101)
G01N 27/49 (20060101)
G01N 30/00 (20060101)
G01N 30/64 (20060101)
G01N 30/34 (20060101)
G01N 30/02 (20060101)

Abstract

An electrochemical detection apparatus is provided. The apparatus comprises a flow-cell having at least one active testing electrode, at least one reference electrode, and at least one counter electrode. Each electrode comprises a liquid impervious solid body having a bore extending therethrough with the electrode active surface located in the bore. The electrodes are arranged in a stack, electrically insulated from one another with their respective bores aligned so as to define a flow channel through which liquid to be detected can be passed. In a preferred embodiment of the invention at least one of the reference electrodes is actively driven to supply a stable reference potential against which other electrochemical responses can be measured. Various electrochemical responses are achieved by varying the construction, number and arrangement of electrodes in the stack, and the potentials applied to the electrodes. The detection apparatus has particular utility for use in monitoring chromatographic eluant.

Other References

  • Donald T. Sawyer et al., "Experimental Electrochemistry for Chemists", pp. 34-48 (1974)
  • H. F. Osswald et al., Chimia, 31, No. 2, (1977)
  • D. G. Swartzfager, Anal. Chem., vol. 48, No. 14, pp. 2189-2192, (1976)
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