Tobramycin-double stranded RNA complex suitable for inducing interferon
Patent 4400375 Issued on August 23, 1983. Estimated Expiration Date: 
November 23, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 23, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3679654 3821193 3845033 Induction of interferon production by modified nucleic acid complexes Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid Patent #: 4349538 InventorsAssigneeApplicationNo. 06/324241 filed on 11/23/1981US Classes:514/34, Oxygen of the saccharide radical bonded directly to a polycyclo ring system of four carbocyclic rings (e.g., daunomycin, etc.)424/85.1, LYMPHOKINE514/889, INTERFERON INDUCER536/16.8, Antibiotics536/23.52, Interferon536/25.5Homopolymers having repeating sequences of four or more identical nucleotide unitsExaminersPrimary: Chan, NickyAttorney, Agent or FirmInternational ClassC07H 21/00 (20060101)AbstractA complex is described which is useful in inducing interferon production, in activating peritoneal macrophages, and in inhibiting the proliferation and migration of tumor cells, which complex comprises natural or synthetic double stranded RNA and tobramycin.Other References
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