U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Zeugmatography process

Patent 4390840 Issued on June 28, 1983. Estimated Expiration Date: Icon_subject November 19, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Gyromagnetic resonance fourier transform zeugmatography
Patent #: 4070611
Issued on: 01/24/1978
Inventor: Ernst

Methods of deriving image information from objects
Patent #: 4290019
Issued on: 09/15/1981
Inventor: Hutchison ,   et al.

Moving gradient zeugmatography Patent #: 4307343
Issued on: 12/22/1981
Inventor: Likes

Inventors

Application

No. 06/208145 filed on 11/19/1980

US Classes:

324/309, To obtain localized resonance within a sample324/318Spectrometer components

Examiners

Primary: Tokar, Michael

Attorney, Agent or Firm

International Classes

G01R 33/36 (20060101)
G01R 33/32 (20060101)
G01R 33/48 (20060101)

Foreign Application Priority Data

1979-12-20 DE

Abstract

In the exemplary embodiments, the imaging of the interior of bodies is rendered possible by means of nuclear magnetic resonance. Up to the present time, the known methods have such a small signal-to-noise ratio that the medical application is uncertain on account of the necessary long measuring duration and the thus unavoidable body movement. The disclosed method permits a significant raising of the signal-to-noise ratio and thus renders possible a shortening of the measuring time for the purpose of preparing medically utilizable images. For this purpose, the disclosure provides, through inversion of the nuclear magnetization by means of "fast adiabatic passage" in the primary field direction and simultaneous detection of the magnetization change by a longitudinal field detector, the attainment of a spatially resolved examination of extensive objects by means of nuclear magnetic resonance (NMR, entire body-zeugmatography) with substantially higher constant field intensities than previously. The signal-to-noise ratio can thereby be increased in the manner desired, and the measuring time can be shortened. The disclosed zeugmatography method is therefore also suitable for medical examinations.

Other References

  • E P. Day, "Detection of NMR Using a Josephson--Junction Magnetometer," Physical Review Letters, vol. 29, No. 9, (1972) pp. 540-542
  • R. A. Webb, "New Technique for Improved Low Temperature SQUID NMR Measurements", Rev. Sci. Instrum., vol. 48, No. 12, Dec. 1977, pp. 1585-1594
  • P. Lauterbur, "Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance", Nature, vol. 242, Mar. 1973, pp. 190-191
  • P. Mansfield and I. L. Pykett, "Biological and Medical Imaging by NMR", Journal of Magnetic Resonance, vol. 29, (1978), pp. 355-373
  • R. Damadian et al., "Field Focusing Nuclear Magnetic Resonance (FONAR): Visualization of a Tumor in a Live Animal", Science, vol. 194, Dec. 1976, pp. 1430-1432
  • W. S. Hinshaw, "Spin Mapping: The Application of Moving Gradients to NMR", Physics Letters, vol. 48A, No. 2, Jun. 1974, pp. 87-88
  • A. Kumar et al., "NMR Fourier Zeugmatography", Journal of Magnetic Resonance, vol. 18, (1975), pp. 69-83
  • Z. Abe et al., "Non-invasive Measurements of Biological Information with Application of Nuclear Magnetic Resonance", C. Thomas Publ., Springfield, IL, (1974)
  • P. A. Bottomley and E. R. Andrew, "RF Magnetic Field Penetration, Phase Shift and Power Dissipation in Biological Tissue: Implications for NMR Imaging", Phys. Med. Biol., vol. 23, No. 4, (1978), pp. 630-643
  • D. I. Hoult and P. Lauterbur, "The Sensitivity of the Zeugmatographic Experiment Involving Human Samples", Journal of Magnetic Resonance, vol. 34, (1979), pp. 425-433
  • D. I. Hoult, R. E. Richards, "V.H.F. F.E.T. Preamplifier With 0.3 dB Noise Figure", Electronic Letters, vol. 11, No. 24, Nov. 1975, pp. 596-597
  • D. I. Hoult, "Rotating Frame Zeugmatography", Journal of Magnetic Resonance, vol. 33, (1979), pp. 183-197
  • G. Schwierz et al., "Principles of Image Reconstruction in X-ray Computer Tomography", Siemens Forsch. u. Entwickl.-Ber., vol. 7, No. 4 (1978), pp. 196-203
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