Patent References 3632740 3731683 InventorsAssigneeApplicationNo. 06/248912 filed on 03/30/1981US Classes:424/449, Transdermal or percutaneous424/448, Pressure sensitive adhesive means424/487, Acrylic acid and derivatives514/420Indomethacine per se or ester thereofExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassesA61L 15/58 (20060101)A61K 9/70 (20060101) A61L 15/16 (20060101) Foreign Application Priority Data1980-10-30 JPAbstractAn antiphlogistic analgesic adhesive which comprisesa flexible substrate andan indomethacin containing pressure-sensitive adhesive layer closely contacting said flexible substrate, wherein said pressure-sensitive adhesive layer comprises a mixture of(a) indomethacin,(b) a copolymer of (i) an alkyl acrylate having 4 to 11 carbon atoms in the alkyl moiety and (ii) a functional monomer having a functional group in the molecule thereof and/or a vinyl monomer, which has pressure-sensitive adhesive properties at room temperature, and(c) an absorption accelerating assistant which maintains said indomethacin in a solubilized state in said copolymer and has skin diffusibility. | |