Imidazo[1,2-a] pyridine derivatives and their application as pharmaceuticals
Patent 4382938 Issued on May 10, 1983. Estimated Expiration Date: 
October 21, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 21, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References3336194 InventorsAssigneeApplicationNo. 06/313601 filed on 10/21/1981US Classes:514/393, Polycyclo ring system having the diazole ring as one of the cyclos544/127, The additional six-membered hetero ring is one of the cyclos in a bicyclo ring system544/362, The additional six-membered hetero ring is one of the cyclos in a bicyclo ring system544/58.4, Having -C(=X)-, wherein X is chalcogen, bonded directly to the thiazine ring546/121Ring nitrogen is shared by the two cyclosExaminersPrimary: Jiles, Henry R.Assistant: Dentz, Bernard Attorney, Agent or FirmInternational ClassesC07D 471/04 (20060101)C07D 471/00 (20060101) Foreign Application Priority Data1980-10-22 FRAbstractImidazo[1,2-a] pyridines of the formula: ##STR1## and their acid addition salts in which Y represents a hydrogen or halogen atom or a C1-4 alkyl radical, Z represents a naphthyl radical or a radical ##STR2## in which each of X1 and X2 independently of one another is a hydrogen or halogen atom, a C1-4 alkoxy radical, a C1-6 alkyl radical or CF3, CH3 S--, CH3 SO2 --, --NO2, --NH2 or --NHCOCH3, and each of R1 and R2 independently of one another represents a hydrogen atom, a straight or branched C1-5 alkyl radical which is unsubstituted or substituted by one or more halogen atoms or hydroxyl, --N(C1-4 alkyl)2, carbamoyl or C1-4 alkoxy radicals, allyl, propargyl, a C3-6 cycloalkyl radical, benzyl, or phenyl, not both R1 and R2 being hydrogen, or --NR1 R2 represents a heterocyclic ring containing from 3 to 6 carbon atoms, or a heterocyclic ring of the formula ##STR3## in which X is O, S, CHOR' or >N--R, R' being hydrogen or benzyl and R being hydrogen, a C1-4 alkyl radical, or phenyl which is unsubstituted or substituted by methoxy or a halogen atom, which may be made from the corresponding acids, have valuable pharmacological properties, especially anxiolytic, anti-anoxic, sleep-inducing, hypnotic and anticonvulsant properties.Other References
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