U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Anti-human T-lymphocyte monoclonal antibody

Patent 4381292 Issued on April 26, 1983. Estimated Expiration Date: Icon_subject November 14, 2000. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of producing antibodies Patent #: 4196265
Issued on: 04/01/1980
Inventor: Koprowski ,   et al.

Inventors

Assignee

Application

No. 06/206915 filed on 11/14/1980

US Classes:

424/154.1, T lymphocytic cell (e.g., T cell, thymocyte, etc.)424/1.53, Attachment via an added element (e.g., bifunctional compound or coordinate, coupling agent, spacer compound, bridging compound, conjugated chelate)424/153.1, Hematopoietic cell435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate435/2, MAINTAINING BLOOD OR SPERM IN A PHYSIOLOGICALLY ACTIVE STATE OR COMPOSITIONS THEREOF OR THEREFOR OR METHODS OF IN VITRO BLOOD CELL SEPARATION OR TREATMENT435/7.24, Leukocyte (e.g., lymphocyte, granulocyte, monocyte, etc.)436/548, Monoclonal antibody530/388.73, Binds lymphocytic or lymphocytic-like cell or component or product thereof (e.g., B cell, B-lineage bone marrow cell, null cell, natural killer cell, B-lymphoblastoid cell, B-lineage acute lymphoblastic leukemia cell, B-lymphocytic cell-surface antigen, etc.)530/388.75, Binds T-lymphocytic cell or component or product thereof (e.g., T cell, thymocyte, T-lineage bone marrow cell, T-lymphoblastoid cell, T-lineage acute lymphoblastic leukemia cell, T-lymphocytic cell-surface antigen, etc.)530/391.3, Conjugated to a detectable label or radioisotope or radionuclide or heavy metal-containing compound530/808MATERIALS AND PRODUCTS RELATED TO GENETIC ENGINEERING OR HYBRID OR FUSED CELL TECHNOLOGY, E.G., HYBRIDOMA, MONOCLONAL PRODUCTS, ETC.

Examiners

Primary: Padgett, Benjamin R.
Assistant: Moskowitz, M.

Attorney, Agent or Firm

International Classes

C07K 16/18 (20060101)
C07K 16/28 (20060101)
G01N 33/569 (20060101)
A61K 38/00 (20060101)

Abstract

Mammalian monoclonal antibodies specific for an antigen diagnostic for thymocytes, normal peripheral T cells and some null cells. The antibodies which distinguish among subpopulations of T cells, find use in assays, cell sorting, and immunosupression.

Other References

  • Eur. J. Immunology 1979, 9:205-210, A. J. McMichael et al., "A Human Thymocyte Antigen Defined by a Hybrid Myeloma Monoclonal Antidoly"
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