U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Dosage for coadministering drug and percutaneous absorption enhancer

Patent 4379454 Issued on April 12, 1983. Estimated Expiration Date: Icon_subject February 17, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3731683

Method and therapeutic system for providing chemotherapy transdermally
Patent #: 4060084
Issued on: 11/29/1977
Inventor: Chandrasekaran ,   et al.

Inert core implant pellet
Patent #: 4096239
Issued on: 06/20/1978
Inventor: Katz ,   et al.

Transdermal delivery of drugs
Patent #: 4230105
Issued on: 10/28/1980
Inventor: Harwood

Therapeutic system for administering drugs to the skin
Patent #: 4286592
Issued on: 09/01/1981
Inventor: Chandrasekaran

Polymeric diffusion matrix containing estradiol diacetate Patent #: 4291014
Issued on: 09/22/1981
Inventor: Keith ,   et al.

Inventors

Assignee

Application

No. 06/235068 filed on 02/17/1981

US Classes:

424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous604/304Bandage, pad, or shield placed on body for sustained treatment thereof

Examiners

Primary: Rosenbaum, C. Fred

Attorney, Agent or Firm

International Class

A61K 9/70 (20060101)

Abstract

A dosage form that coadministers a drug and a percutaneous absorption enhancer to a defined area of the skin. The dosage form comprises a body that contains supplies of drug and enhancer and has a basal surface that contacts the area of skin and transmits the drug and enhancer to the area for absorption thereby. The drug is provided to the basal surface at a rate at least as great as the rate at which the skin is able to absorb the drug whereas the enhancer is via a rate controlling means at a substantially constant rate that increases the permeability of the treated area of skin to the drug to a level at which the drug is absorbed at a therapeutically effective rate.

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