5-ASA Drug delivery system
Patent 4374932 Issued on February 22, 1983. Estimated Expiration Date: 
June 8, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 8, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2697059 2721827 2990332 3143465 InventorsAssigneeApplicationNo. 06/271748 filed on 06/08/1981US Classes:521/32, Treated with nitrogen-containing material424/78.12, Adsorbate or treating agent contains nitrogen424/78.16, Amine containing aromatic group514/166, Nitrogen containing (e.g., anilides, etc.)521/28Previously formed solid ion-exchange polymer admixed with nonreactive material or ion-exchange polymerExaminersPrimary: Schofer, Joseph L.Assistant: Kulkosky, Peter F. Attorney, Agent or FirmInternational ClassesA61K 47/48 (20060101)C07C 245/00 (20060101) C07C 245/08 (20060101) AbstractThe present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid. | |
