U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose

Patent 4369172 Issued on January 18, 1983. Estimated Expiration Date: Icon_subject December 18, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2887440

3065143

3839319

3852421

3870790

4091205

Novel sustained release tablet formulations
Patent #: 4167558
Issued on: 09/11/1979
Inventor: Sheth ,   et al.

Sustained release therapeutic compositions
Patent #: 4226849
Issued on: 10/07/1980
Inventor: Schor

Method and composition for the preparation of controlled long-acting pharmaceuticals
Patent #: 4259314
Issued on: 03/31/1981
Inventor: Lowey

Controlled release suppositories
Patent #: 4265875
Issued on: 05/05/1981
Inventor: Byrne ,   et al.

More ...

Inventors

Assignee

Application

No. 06/332348 filed on 12/18/1981

US Classes:

424/468, Sustained or differential release type424/430, Vaginal, urethral, uterine424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/480, Cellulose or derivative514/781Cellulose or derivative

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Class

A61K 9/20 (20060101)

Abstract

A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxypropylmethylcellulose has a hydroxypropoxyl content of 9-12 weight % and a number average molecular weight of less than 50,000.

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