Patent References3523807 InventorsApplicationNo. 06/118529 filed on 02/04/1980US Classes:106/124.51, With carbohydrate from an external source106/146.4, With nonproteinaceous organic compound containing sulfur or nitrogen514/21, Produced by or extracted from animal tissue530/380, Blood proteins or globulins, e.g., proteoglycans, platelet factor 4, thyroglobulin, thyroxine, etc.530/382, Fibrin or fibrin intermediates, e.g., fibrinogen, etc.530/383Blood coagulation factor VIII, AHFExaminersPrimary: Lieberman, Allan M.Attorney, Agent or FirmInternational ClassesA61K 38/00 (20060101)A61L 24/00 (20060101) A61L 24/10 (20060101) Foreign Application Priority Data1979-02-15 ATAbstractA tissue adhesive on the basis of human or animal protein contains factor XIII and at least 33% by weight of fibrinogen, has a ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, of at least 80, contains fibrinogen and albumin in the total protein at a ratio of 33 to 90:5 to 40, contains plasminogen-activator-inhibitor or plasmin inhibitor in an amount of 250 to 25,000 KIU per g of fibrinogen and has been lyophilized. |
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