Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres
Patent 4357259 Issued on November 2, 1982. Estimated Expiration Date: 
November 2, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 2, 1999. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2989417 3137631 3474777 3663687 Method for incorporating substances into protein microspheres Patent #: 3937668 InventorsAssigneeApplicationNo. 05/859842 filed on 12/12/1977US Classes:264/4.3, With treatment subsequent to solid wall formation (e.g., coating, hardening, etc.)252/62.53, With wax, bitumen, resin, or gum252/62.54, Synthetic resin424/1.37, Radionuclide or intended radionuclide in an organic compound424/450, Liposomes424/490, Coated (e.g., microcapsules)424/499, Contains proteins or derivative or polysaccharides or derivative424/9.1, IN VIVO DIAGNOSIS OR IN VIVO TESTING424/9.322, Polymer containing (e.g., polypeptide, synthetic resin, etc.)427/338, Proteinaceous coating514/776Albumin or derivativeExaminersPrimary: Lovering, Richard D.International ClassesA61K 41/00 (20060101)A61K 9/16 (20060101) A61K 49/06 (20060101) A61K 49/18 (20060101) A61K 9/50 (20060101) AbstractA method is provided for incorporating water-soluble therapeutic agents in albumin microspheres. This method is particularly advantageous where the therapeutic agent is heat-sensitive. All steps of the method can be carried out at relatively low temperatures, such as ambient room temperature. The method may be applied to the preparation of intravascularly-administrable, magnetically-responsive microspheres.Other References
| |
