Process for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant
Patent 4347236 Issued on August 31, 1982. Estimated Expiration Date: 
May 19, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 19, 2001. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesBeclomethasone dipropionate-hexane solvate and aerosols prepared therefrom Patent #: 4225597 InventorAssigneeApplicationNo. 06/265333 filed on 05/19/1981US Classes:424/45, Organic pressurized fluid514/179Modified C-ring (except methyl in 13-position) (e.g., double bond containing, substituted, etc.)ExaminersPrimary: Roberts, Elbert L.Attorney, Agent or FirmInternational ClassC09K 3/30 (20060101)Foreign Application Priority Data1980-05-19 FIAbstractA process by means of which an increase in the particle size of a micro-ground anti-inflammatory steroid in the aerosol propellant is prevented. The increase in the particle size is prevented at the suspending stage when the solubility of the steroid into the propellant is reduced by using a low temperature and by initially mixing only a little quantity of the propellant with the steroid. If desired, the smallest and dissolved steroid particles can be removed by filtering. The particle size does not become larger even afterwards when the suspension is allowed to be stabilized for a sufficiently long time before the temperature is raised or the rest of the propellant is added.Other References
Field of SearchOrganic pressurized fluid | |
